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The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing.

The C terminus of nuclear hormone receptors is a complex structure that contains multiple functions. We are interested in the mechanism by which thyroid hormone converts its receptor from a transcriptional silencer to an activator of transcription. Both regulatory functions are localized in the liga...

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Autors principals: Baniahmad, A, Leng, X, Burris, T P, Tsai, S Y, Tsai, M J, O'Malley, B W
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC231910/
https://ncbi.nlm.nih.gov/pubmed/7799971
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