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Monocyte expression of the human prointerleukin 1 beta gene (IL1B) is dependent on promoter sequences which bind the hematopoietic transcription factor Spi-1/PU.1.

Interleukin-1 beta (IL-1 beta) is produced primarily by stimulated monocytes, suggesting that the IL1B gene, which codes for this protein, depends upon at least one cell-type-specific factor. Our previous characterization of the IL1B promoter indicated that the region between -131 and +12 is suffici...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Kominato, Y, Galson, D, Waterman, W R, Webb, A C, Auron, P E
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 1995
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231908/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7799967/
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