Repression of gonadotropin-releasing hormone promoter activity by the POU homeodomain transcription factor SCIP/Oct-6/Tst-1: a regulatory mechanism of phenotype expression?

POU domain transcription factors are required for neuropeptide expression in selected subsets of hypothalamic neuroendocrine neurons. We now report that expression of the gonadotropin-releasing hormone (GnRH) gene, which controls sexual development, is regulated by the POU protein SCIP/Oct-6/Tst-1....

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Wierman, M E, Xiong, X, Kepa, J K, Spaulding, A J, Jacobsen, B M, Fang, Z, Nilaver, G, Ojeda, S R
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1997
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231890/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032292/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.3.1652
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