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Hodgkin and Reed–Sternberg cells in lymphocyte predominant Hodgkin disease represent clonal populations of germinal center-derived tumor B cells

Among the four subtypes of Hodgkin disease (HD), lymphocyte-predominant (LP) HD is now generally considered as a separate entity. The B cell nature of the typical Hodgkin and Reed–Sternberg (HRS) cells and their variants (L and H, lymphocytic and histiocytic cells) in LP HD has long been suspected,...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Braeuninger, Andreas, Küppers, Ralf, Strickler, John G., Wacker, Hans-Heinrich, Rajewsky, Klaus, Hansmann, Martin-Leo
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23186/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9256483/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.17.9337
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