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A severely defective TATA-binding protein-TFIIB interaction does not preclude transcriptional activation in vivo.

In yeast cells, mutations in the TATA-binding protein (TBP) that disrupt the interaction with the TATA element or with TFIIA can selectively impair the response to acidic activator proteins. We analyzed the transcriptional properties of TBP derivatives in which residues that directly interact with T...

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Main Authors: Lee, M, Struhl, K
格式: Artigo
語言:Inglês
出版: 1997
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC231858/
https://ncbi.nlm.nih.gov/pubmed/9032260
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