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Negative protein 1, which is required for function of the chicken lysozyme gene silencer in conjunction with hormone receptors, is identical to the multivalent zinc finger repressor CTCF.

The transcriptional repressor negative protein 1 (NeP1) binds specifically to the F1 element of the chicken lysozyme gene silencer and mediates synergistic repression by v-ERBA, thyroid hormone receptor, or retinoic acid receptor. Another protein, CCCTC-binding factor (CTCF), specifically binds to 5...

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Bibliografiske detaljer
Main Authors: Burcin, M, Arnold, R, Lutz, M, Kaiser, B, Runge, D, Lottspeich, F, Filippova, G N, Lobanenkov, V V, Renkawitz, R
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC231853/
https://ncbi.nlm.nih.gov/pubmed/9032255
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