Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes.

The family of p21-activated protein kinases (PAKs) appear to be present in all organisms that have Cdc42-like GTPases. In mammalian cells, PAKs have been implicated in the activation of mitogen-activated protein kinase cascades, but there are no reported effects of these kinases on the cytoskeleton....

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Pubblicato in:	Mol Cell Biol
Autori principali:	Manser, E, Huang, H Y, Loo, T H, Chen, X Q, Dong, J M, Leung, T, Lim, L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231838/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032240/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.3.1129
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