Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stability.

The p53 tumor suppressor protein is activated in cells in response to DNA damage and prevents the replication of cells sustaining genetic damage by inducing a cell cycle arrest or apoptosis. Activation of p53 is accompanied by stabilization of the protein, resulting in accumulation to high levels wi...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Kubbutat, M H, Vousden, K H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231771/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972227/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.1.460
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