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Localization of BRCA1 and a splice variant identifies the nuclear localization signal.

Inherited mutations in BRCA1 confer susceptibility to breast and ovarian neoplasms. However, the function of BRCA1 and the role of BRCA1 in noninherited cancer remain unknown. Characterization of alternately spliced forms of BRCA1 may identify functional regions; thus, we constructed expression vect...

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Detalhes bibliográficos
Main Authors: Thakur, S, Zhang, H B, Peng, Y, Le, H, Carroll, B, Ward, T, Yao, J, Farid, L M, Couch, F J, Wilson, R B, Weber, B L
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231769/
https://ncbi.nlm.nih.gov/pubmed/8972225
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