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The carboxy-terminal transactivation domain of Oct-4 acquires cell specificity through the POU domain.

The POU transcription factor Oct-4 is expressed in totipotent and pluripotent cells of the early mouse embryo and the germ cell lineage. Transactivation capacities of regions flanking the DNA binding domain of Oct-4 were analyzed in undifferentiated and differentiated cell lines. The amino- and carb...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Brehm, A, Ohbo, K, Schöler, H
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231739/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972195/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.1.154
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