p53 inhibits RNA polymerase III-directed transcription in a promoter-dependent manner.

Wild-type p53 represses Alu template activity in vitro and in vivo. However, upstream activating sequence elements from both the 7SL RNA gene and an Alu source gene relieve p53-mediated repression. p53 also represses the template activity of the U6 RNA gene both in vitro and in vivo but has no effec...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Chesnokov, I, Chu, W M, Botchan, M R, Schmid, C W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231711/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943363/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.7084
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