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Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene.

The interleukin 2 receptor alpha-chain (IL-2R alpha) gene is a key regulator of lymphocyte proliferation. IL-2R alpha is rapidly and potently induced in T cells in response to mitogenic stimuli. Interleukin 2 (IL-2) stimulates IL-2R alpha. transcription, thereby amplifying expression of its own high...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Lécine, P, Algarté, M, Rameil, P, Beadling, C, Bucher, P, Nabholz, M, Imbert, J
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1996
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231686/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943338/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.6829
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