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Abnormal development of secondary lymphoid tissues in lymphotoxin β-deficient mice

The tumor necrosis factor (TNF) family cytokines lymphotoxin (LT) α and LTβ form heterotrimers that are expressed on the surface of activated lymphocytes and natural killer cells; LTα homotrimers can be secreted as well. Mice with a disrupted LTα gene lack lymph nodes (LN), Peyer’s patches (PP), and...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Alimzhanov, Marat B., Kuprash, Dmitry V., Kosco-Vilbois, Marie H., Luz, Arne, Turetskaya, Regina L., Tarakhovsky, Alexander, Rajewsky, Klaus, Nedospasov, Sergei A., Pfeffer, Klaus
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23168/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9256477/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.17.9302
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