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ERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologs.

ERCC4 is an essential human gene in the nucleotide excision repair (NER) pathway, which is responsible for removing UV-C photoproducts and bulky adducts from DNA. Among the NER genes, ERCC4 and ERCC1 are also uniquely involved in removing DNA interstrand cross-linking damage. The ERCC1-ERCC4 heterod...

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Bibliographic Details
Main Authors: Brookman, K W, Lamerdin, J E, Thelen, M P, Hwang, M, Reardon, J T, Sancar, A, Zhou, Z Q, Walter, C A, Parris, C N, Thompson, L H
Format: Artigo
Language:Inglês
Published: 1996
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC231657/
https://ncbi.nlm.nih.gov/pubmed/8887684
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