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The mating-specific G(alpha) protein of Saccharomyces cerevisiae downregulates the mating signal by a mechanism that is dependent on pheromone and independent of G(beta)(gamma) sequestration.

It has been inferred from compelling genetic evidence that the pheromone-responsive G(alpha) protein of Saccharomyces cerevisiae, Gpa1, directly inhibits the mating signal by binding to its own beta(gamma) subunit. Gpa1 has also been implicated in a distinct but as yet uncharacterized negative regul...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Stratton, H F, Zhou, J, Reed, S I, Stone, D E
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231635/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8887662/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.11.6325
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