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Interferon regulatory factors and TFIIB cooperatively regulate interferon-responsive promoter activity in vivo and in vitro.

Interferon regulatory factors (IRFs) bind to the interferon-stimulated response element (ISRE) and regulate interferon- and virus-mediated gene expression. IRF-1 acts as a transcriptional activator, while IRF-2 acts as a repressor. Here we show that IRF-1 and IRF-2 bind to both cellular TFIIB, a com...

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Udgivet i:Mol Cell Biol
Principais autores: Wang, I M, Blanco, J C, Tsai, S Y, Tsai, M J, Ozato, K
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231634/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8887661/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.11.6313
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