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A suboptimal 5' splice site is a cis-acting determinant of nuclear export of polyomavirus late mRNAs.

Mouse polyomavirus has been used as a model system to study nucleocytoplasmic transport of mRNA. Three late mRNAs encoding the viral capsid proteins are generated by alternative splicing from common pre-mRNA molecules. mRNAs encoding the virion protein VP2 (mVP2) harbor an unused 5' splice site, and...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Huang, Y, Carmichael, G G
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231607/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8887634/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.11.6046
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