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Length changes in the joining segment between domains 5 and 6 of a group II intron inhibit self-splicing and alter 3' splice site selection.

Domain 5 (D5) and domain 6 (D6) are adjacent folded hairpin substructures of self-splicing group II introns that appear to interact within the active ribozyme. Here we describe the effects of changing the length of the 3-nucleotide segment joining D5 to D6 [called J(56)3] on the splicing reactions o...

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Udgivet i:Mol Cell Biol
Principais autores: Boulanger, S C, Faix, P H, Yang, H, Zhuo, J, Franzen, J S, Peebles, C L, Perlman, P S
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231591/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816503/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.10.5896
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