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Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity
Caspase-1 and caspase-11 are proinflammatory caspases that regulate cytokine production and leukocyte migration during pathogen infection. In an attempt to identify new intracellular regulators of caspase-11, we found that Flightless-I, a member of the gelsolin superfamily of actin-remodeling protei...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2315678/ https://ncbi.nlm.nih.gov/pubmed/18411310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200711082 |
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