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Ca2+-calmodulin promotes survival of pheromone-induced growth arrest by activation of calcineurin and Ca2+-calmodulin-dependent protein kinase.

The cmd1-6 allele contains three mutations that block Ca2+ binding to calmodulin from Saccharomyces cerevisiae. We find that strains containing cmd1-6 lose viability during cell cycle arrest induced by the mating pheromone alpha-factor. The 50% lethal dose (LD50) of alpha-factor for the calmodulin m...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Moser, M J, Geiser, J R, Davis, T N
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231484/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8756641/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.9.4824
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