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Dephosphorylation of threonine 169 of Cdc28 is not required for exit from mitosis but may be necessary for start in Saccharomyces cerevisiae.

Entry into mitosis requires activation of cdc2 kinase brought on by its association with cyclin B, phosphorylation of the conserved threonine (Thr-167 in Schizosaccharomyces pombe) in the T loop, and dephosphorylation of the tyrosine residue at position 15. Exit from mitosis, on the other hand, is i...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Lim, H H, Loy, C J, Zaman, S, Surana, U
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1996
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231456/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8754858/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.8.4573
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