Interaction of the interferon-induced PKR protein kinase with inhibitory proteins P58IPK and vaccinia virus K3L is mediated by unique domains: implications for kinase regulation.

Expression of the double-stranded RNA-activated protein kinase (PKR) is induced by interferons, with PKR activity playing a pivotal role in establishing the interferon-induced antiviral and antiproliferative states. PKR is directly regulated by physical association with the specific inhibitor, P58IP...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Gale, M, Tan, S L, Wambach, M, Katze, M G
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231414/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8754816/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.8.4172
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