Two regions within the DNA binding domain of nuclear factor I interact with DNA and stimulate adenovirus DNA replication independently.

The cellular transcription factor nuclear factor I (NFI) stimulates adenovirus DNA replication by up to 50-fold. The NFI DNA binding domain (NFI-BD) is sufficient for stimulation and interacts with the viral DNA polymerase, thereby recruiting the precursor terminal protein-DNA polymerase complex (pT...

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Bibliografiska uppgifter

I publikationen:	Mol Cell Biol
Huvudupphov:	Dekker, J, van Oosterhout, J A, van der Vliet, P C
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Taylor & Francis 1996
Ämnen:	Research Article
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231403/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8754805/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.8.4073
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