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Functional mapping of the translation-dependent instability element of yeast MATalpha1 mRNA.

The determinants of mRNA stability include specific cis-acting destabilizing sequences located within mRNA coding and noncoding regions. We have developed an approach for mapping coding-region instability sequences in unstable yeast mRNAs that exploits the link between mRNA translation and turnover...

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Autors principals: Hennigan, A N, Jacobson, A
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC231380/
https://ncbi.nlm.nih.gov/pubmed/8668201
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