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Evidence of evolutionary up-regulation of the single active X chromosome in mammals based on Clc4 expression levels in Mus spretus and Mus musculus

Previous studies have shown that the chloride channel gene Clc4 is X-linked and subject to X inactivation in Mus spretus, but that the same gene is autosomal in laboratory strains of mice. This exception to the conservation of linkage of the X chromosome in one of two interfertile mouse species was...

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Autors principals: Adler, David A., Rugarli, Elena I., Lingenfelter, Patricia A., Tsuchiya, Karen, Poslinski, Diane, Liggitt, H. Denny, Chapman, Verne M., Elliott, Rosemary W., Ballabio, Andrea, Disteche, Christine M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC23138/
https://ncbi.nlm.nih.gov/pubmed/9256467
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