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Non-Mendelian, heritable blocks to DNA rearrangement are induced by loading the somatic nucleus of Tetrahymena thermophila with germ line-limited DNA.

Site-specific DNA deletion occurs at thousands of sites within the genome during macronuclear development of Tetrahymena thermophila. These deletion elements are usually not detected in macronuclear chromosomes. We have interfered with the normal deletion of two of these elements, the adjacent M and...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Chalker, D L, Yao, M C
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1996
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231361/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8668182/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.7.3658
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