Yeast pip3/mec3 mutants fail to delay entry into S phase and to slow DNA replication in response to DNA damage, and they define a functional link between Mec3 and DNA primase.

The catalytic DNA primase subunit of the DNA polymerase alpha-primase complex is encoded by the essential PRI1 gene in Saccharomyces cerevisiae. To identify factors that functionally interact with yeast DNA primase in living cells, we developed a genetic screen for mutants that are lethal at the per...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Longhese, M P, Fraschini, R, Plevani, P, Lucchini, G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231317/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8668138/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.7.3235
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