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The activity of the highly inducible mouse phenylalanine hydroxylase gene promoter is dependent upon a tissue-specific, hormone-inducible enhancer.

Expression of the phenylalanine hydroxylase gene in livers and kidneys of rodents is activated at birth and is induced by glucocorticoids and cyclic AMP in the liver. Regulatory elements in a 10-kb fragment upstream of the mouse gene have been characterized. The promoter lacks TAATA and CCAAT consen...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Faust, D M, Catherin, A M, Barbaux, S, Belkadi, L, Imaizumi-Scherrer, T, Weiss, M C
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231307/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8649424/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.6.3125
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