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Adeno-associated virus (AAV) site-specific integration: Formation of AAV–AAVS1 junctions in an in vitro system

An in vitro system to study the mechanism of site-specific integration of adeno-associated virus (AAV) was developed. This system is based on two substrates, a linear or circular AAV donor and a circular acceptor containing the preintegration locus AAVS1. In the presence of HeLa extract and the His-...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Dyall, Julie, Szabo, Paul, Berns, Kenneth I.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23128/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10536011/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.22.12849
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