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Attenuation of virulence in Mycobacterium tuberculosis expressing a constitutively active iron repressor

Iron is an essential nutrient for the survival of most organisms and has played a central role in the virulence of many infectious disease pathogens. Mycobacterial IdeR is an iron-dependent repressor that shows 80% identity in the functional domains with its corynebacterial homologue, DtxR (diphther...

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Bibliographische Detailangaben
Hauptverfasser: Manabe, Yukari C., Saviola, Beatrice J., Sun, Li, Murphy, John R., Bishai, William R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC23125/
https://ncbi.nlm.nih.gov/pubmed/10536010
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