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Interplay between hydrophobic cluster and loop propensity in β-hairpin formation: A mechanistic study

We investigated the structural determinants of the stability of a designed β-hairpin containing a natural hydrophobic cluster from the protein GB1 and a D-Pro-Gly turn forming sequence. The results of our simulations shed light on the factors leading to an ordered secondary structure in a model pept...

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Bibliografske podrobnosti
Main Authors: Colombo, Giorgio, De Mori, Giacomo M.S., Roccatano, Danilo
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312445/
https://ncbi.nlm.nih.gov/pubmed/12592024
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