Tethered Sir3p nucleates silencing at telomeres and internal loci in Saccharomyces cerevisiae.

Rap1p binds to sites embedded within the Saccharomyces cerevisiae telomeric TG1-3 tract. Previous studies have led to the hypothesis that Rap1p may recruit Sir3p and Sir3p-associating factors to the telomere. To test this, we tethered Sir3p adjacent to the telomere via LexA binding sites in the rap1...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Lustig, A J, Liu, C, Zhang, C, Hanish, J P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231237/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628316/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.5.2483
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