Functional regions of the mouse thrombopoietin receptor cytoplasmic domain: evidence for a critical region which is involved in differentiation and can be complemented by erythropoietin.

Thrombopoietin (TPO) is the major regulator of growth and differentiation of megakaryocytes. To identify functionally important regions in the cytoplasmic domain of the TPO receptor, mpl, we introduced wild-type mpl and deletion mutants of murine mpl into the granulocyte-macrophage colony-stimulatin...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Porteu, F, Rouyez, M C, Cocault, L, Bénit, L, Charon, M, Picard, F, Gisselbrecht, S, Souyri, M, Dusanter-Fourt, I
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231236/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628315/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.5.2473
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