A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit.
Transcription factor NF-kappaB is generally considered to be a heterodimer with two subunits, p50 and p65. The p50 subunit has been suggested to be generated from its precursor, p105, via the ubiquitin-proteasome pathway. During processing, the C-terminal portion of p105 is rapidly degraded whereas...
Gespeichert in:
| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1996
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628291/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.5.2248 |
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