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Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes.

The Wnt-1 proto-oncogene induces the accumulation of beta-catenin and plakoglobin, two related proteins that associate with and functionally modulate the cadherin cell adhesion proteins. Here we have investigated the effects of Wnt-1 expression on the tumor suppressor protein APC, which also associa...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Papkoff, J, Rubinfeld, B, Schryver, B, Polakis, P
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231200/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628279/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.5.2128
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