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Binding of the Ets factor GA-binding protein to an upstream site in the factor IX promoter is a critical event in transactivation.

Factor IX is an essential vitamin K-dependent serine protease that participates in the intrinsic pathway of coagulation. The protein is expressed exclusively in the liver. The rare Leyden form of hemophilia B (inherited factor IX deficiency) results from point mutations in three proximal promoter el...

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Detalhes bibliográficos
Main Authors: Boccia, L M, Lillicrap, D, Newcombe, K, Mueller, C R
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231180/
https://ncbi.nlm.nih.gov/pubmed/8628259
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