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Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus.

Pbx cofactors are implicated to play important roles in modulating the DNA-binding properties of heterologous homeodomain proteins, including class I Hox proteins. To assess how Pbx proteins influence Hox DNA-binding specificity, we used a binding-site selection approach to determine high-affinity t...

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Udgivet i:Mol Cell Biol
Principais autores: Chang, C P, Brocchieri, L, Shen, W F, Largman, C, Cleary, M L
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231160/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8657149/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.4.1734
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