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Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus.

Pbx cofactors are implicated to play important roles in modulating the DNA-binding properties of heterologous homeodomain proteins, including class I Hox proteins. To assess how Pbx proteins influence Hox DNA-binding specificity, we used a binding-site selection approach to determine high-affinity t...

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Bibliografische gegevens
Hoofdauteurs: Chang, C P, Brocchieri, L, Shen, W F, Largman, C, Cleary, M L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC231160/
https://ncbi.nlm.nih.gov/pubmed/8657149
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