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The Niemann-Pick C1 gene is downregulated by feedback inhibition of the SREBP pathway in human fibroblasts
The Niemann-Pick C1 (NPC1) protein regulates the transport of cholesterol from late endosomes/lysosomes to other compartments responsible for maintaining intracellular cholesterol homeostasis. The present study examined the expression of the NPC1 gene and the distribution of the NPC1 protein that re...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2311449/ https://ncbi.nlm.nih.gov/pubmed/18272927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M700555-JLR200 |
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