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Rational chemical design of the carbohydrate in a glycoconjugate vaccine enhances IgM-to-IgG switching
Many pathogens are sheltered from host immunity by surface polysaccharides that would be ideal as vaccines except that they are too similar to host antigens to be immunogenic. The production of functional IgG is a desirable response to vaccines; because IgG is the only isotype that crosses the place...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2311338/ https://ncbi.nlm.nih.gov/pubmed/18378894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710799105 |
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