The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells.

We are employing recent advances in the understanding of the cell cycle to study the inverse relationship between proliferation and neuronal differentiation. Nerve growth factor and aphidicolin, an inhibitor of DNA polymerases, synergistically induce neuronal differentiation of SH-SY5Y neuroblastoma...

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Autors principals: Poluha, W, Poluha, D K, Chang, B, Crosbie, N E, Schonhoff, C M, Kilpatrick, D L, Ross, A H
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC231117/
https://ncbi.nlm.nih.gov/pubmed/8657106
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