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Functional dissection of the human Bcl2 protein: sequence requirements for inhibition of apoptosis.

Overexpression of the cytoplasmic oncoprotein Bcl2 blocks programmed cell death (apoptosis) in many cellular systems. To map the sequences in Bcl2 that are necessary for its activity, we created a library of deletion-scanning mutants of this 239-amino-acid protein and tested their abilities to block...

詳細記述

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書誌詳細
主要な著者: Hunter, J J, Bond, B L, Parslow, T G
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC231068/
https://ncbi.nlm.nih.gov/pubmed/8622689
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