p21 Disrupts the interaction between cdk2 and the E2F-p130 complex.

In nonproliferating or growth-arrested cells, the transcription factor E2F remains bound to the retinoblastoma-related protein p130. Accumulation of this E2F-p130 complex correlates with an arrest of the cell cycle progression. Progression through G1 phase is associated with a cyclin-dependent bindi...

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Detalhes bibliográficos
Main Authors: Shiyanov, P, Bagchi, S, Adami, G, Kokontis, J, Hay, N, Arroyo, M, Morozov, A, Raychaudhuri, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231053/
https://ncbi.nlm.nih.gov/pubmed/8622674
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