Yeast nucleoporin mutants are defective in pre-tRNA splicing.
We have screened nucleoporin mutants for the inhibition of tRNA splicing, which has previously been proposed to be coupled to transport. Strains mutant for Nup49p or Nup116p, or genetically depleted of Nup145p, strongly accumulated unspliced pre-tRNAs. Splicing was inhibited for all 10 families of i...
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| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1996
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231003/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524308/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.1.294 |
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