DNA immunization circumvents deficient induction of T helper type 1 and cytotoxic T lymphocyte responses in neonates and during early life

The relative deficiency of T helper type 1 (Th1) and cytotoxic T lymphocyte (CTL) responses in early life is associated with an increased susceptibility to infections by intracellular microorganisms. This is likely to reflect a preferential polarization of immature CD4 T cells toward a Th2 rather th...

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Bibliografske podrobnosti
Main Authors: Martinez, Xavier, Brandt, Christian, Saddallah, Fatiha, Tougne, Chantal, Barrios, Christy, Wild, Fabian, Dougan, Gordan, Lambert, Paul-Henri, Siegrist, Claire-Anne
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences of the USA 1997
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC23100/
https://ncbi.nlm.nih.gov/pubmed/9238045
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