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Met30p, a yeast transcriptional inhibitor that responds to S-adenosylmethionine, is an essential protein with WD40 repeats.

A specific repression mechanism regulates the biosynthesis of sulfur amino acids in Saccharomyces cerevisiae. When the intracellular S-adenosylmethionine (AdoMet) concentration increases, transcription of the sulfur genes is repressed. Using a specific reporter system, we have isolated mutations imp...

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Bibliographic Details
Main Authors: Thomas, D, Kuras, L, Barbey, R, Cherest, H, Blaiseau, P L, Surdin-Kerjan, Y
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC230905/
https://ncbi.nlm.nih.gov/pubmed/8524217
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