Role of EGR-1 in thapsigargin-inducible apoptosis in the melanoma cell line A375-C6.

Induction of apoptosis by diverse exogenous signals is dependent on elevation of intracellular Ca2+. This process of cell death can be blocked by actinomycin D, indicating that it requires gene transcription events. To identify genes that are required for apoptosis, we used thapsigargin (TG), which...

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Main Authors: Muthukkumar, S, Nair, P, Sells, S F, Maddiwar, N G, Jacob, R J, Rangnekar, V M
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC230878/
https://ncbi.nlm.nih.gov/pubmed/7565779
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