Role of EGR-1 in thapsigargin-inducible apoptosis in the melanoma cell line A375-C6.

Induction of apoptosis by diverse exogenous signals is dependent on elevation of intracellular Ca2+. This process of cell death can be blocked by actinomycin D, indicating that it requires gene transcription events. To identify genes that are required for apoptosis, we used thapsigargin (TG), which...

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Bibliographic Details
Main Authors: Muthukkumar, S, Nair, P, Sells, S F, Maddiwar, N G, Jacob, R J, Rangnekar, V M
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC230878/
https://ncbi.nlm.nih.gov/pubmed/7565779
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