Role of EGR-1 in thapsigargin-inducible apoptosis in the melanoma cell line A375-C6.

Induction of apoptosis by diverse exogenous signals is dependent on elevation of intracellular Ca2+. This process of cell death can be blocked by actinomycin D, indicating that it requires gene transcription events. To identify genes that are required for apoptosis, we used thapsigargin (TG), which...

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Main Authors: Muthukkumar, S, Nair, P, Sells, S F, Maddiwar, N G, Jacob, R J, Rangnekar, V M
Formato: Artigo
Idioma:Inglês
Publicado: 1995
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC230878/
https://ncbi.nlm.nih.gov/pubmed/7565779
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