Transcriptional activation of the Epstein-Barr virus latency C promoter after 5-azacytidine treatment: evidence that demethylation at a single CpG site is crucial.

The Epstein-Barr Virus (EBV) latency C promoter (Cp) is the origin of transcripts for six viral proteins. The promoter is active in lymphoblastoid B-cell lines but silent in many EBV-associated tumors and tumor cell lines. In these latter cell lines, the viral episome is hypermethylated in the vicin...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Robertson, K D, Hayward, S D, Ling, P D, Samid, D, Ambinder, R F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230866/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565767/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.11.6150
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