Nuclear localization of v-Abl leads to complex formation with cyclic AMP response element (CRE)-binding protein and transactivation through CRE motifs.

Deregulated expression of v-abl and BCR/abl genes has been associated with myeloproliferative syndromes and myelodysplasia, both of which can progress to acute leukemia. These studies identify the localization of the oncogenic form of the abl gene product encoded by the Abelson murine leukemia virus...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Birchenall-Roberts, M C, Ruscetti, F W, Kasper, J J, Bertolette, D C, Yoo, Y D, Bang, O S, Roberts, M S, Turley, J M, Ferris, D K, Kim, S J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1995
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC230860/
https://ncbi.nlm.nih.gov/pubmed/7565761
Tagiau: Ychwanegu Tag
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