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Casein kinase II phosphorylation site mutations in c-Myb affect DNA binding and transcriptional cooperativity with NF-M.

Phosphorylation of c-Myb has been implicated in the regulation of the binding of c-Myb to DNA. We show that murine c-Myb is phosphorylated at Ser-11 and -12 in vivo and that these sites can be phosphorylated in vitro by casein kinase II (CKII), analogous to chicken c-Myb. An efficient method to stud...

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Publicat a:Mol Cell Biol
Autors principals: Oelgeschläger, M, Krieg, J, Lüscher-Firzlaff, J M, Lüscher, B
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230848/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565749/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.11.5966
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