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Widely spaced, directly repeated PuGGTCA elements act as promiscuous enhancers for different classes of nuclear receptors.

We describe here a novel class of cis-acting response elements for retinoid, vitamin D, and estrogen receptors which are widely spaced (10 to 200 bp) direct repeats (DRs) of the canonical 5'-AGGTCA half-site recognition motif (DR10 to DR200). In contrast to the specificity previously observed w...

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Autors principals: Kato, S, Sasaki, H, Suzawa, M, Masushige, S, Tora, L, Chambon, P, Gronemeyer, H
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC230837/
https://ncbi.nlm.nih.gov/pubmed/7565738
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